Dominguez-Martinez M, Caro-Llopis A, Martin-Grau C, Rosello M, Oltra S, Pedrola L, Monfort S, Gabaldon-Albero A, Martinez F, Orellana C
Graphical Abstract Similar content being viewed by others Abbreviations DLAT : Dihydrolipoamide S-acetyltransferase FDX1: Ferredoxin 1 GCLC: Glutamate-cysteine ligase catalytic subunit ICB: Immune checkpoint blockade ICD: Immunogenic cell death L-BSO: L-Buthionine-(S,R)-sulfoximine LIAS: Lipoic acid synthetase SLC31A1: Solute carrier family 31 TIME: Tumor immune microenvironment TNBC: Triple-negative breast cancer Funding This work was supported by the National Key Clinical Specialty Construction Program, the Science and Technology Program of Chengdu (2024-YF05-00487-SN), the Science and Technology Program of Tibet Autonomous Region (XZ202401RK0005), the Sichuan Science and Technology program (2023YFS0133), the Natural Science Foundation of Xiamen Municipality (3502Z202374035)
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People wondering whether GLP-1 is the same as Ozempic should understand that Ozempic is one specific GLP-1 agonist among several, each with its own pharmacological profile and clinical data
Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl-p53 pathway