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Asthma exacerbation has been reported in sensitive individuals, particularly with inhaled formulations

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Srinivasan, R., Ratiney, H., Hammond-Rosenbluth, K

Protein Nitration and DNA Oxidation Increase in DBA Retinas Protein nitration due to oxidative stress occurs when nitric oxide and oxygen radicals combine to form peroxynitrite, which leaves a footprint that can be detected using antibodies to 3-nitrotyrosine (3-NT) [48]