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Human GMSCs treated with AEDG peptide showed an upregulation of all the genes in question and proteins: Nestin, GAP43, Tubulin III and Doublecortin (Figure 3 and Figure 4)

de Boer, F

It is thought to down-regulate inflammatory molecules (cytokines) and up-regulate antioxidant enzymes

Understanding these mechanisms provides insight into how this peptide produces its body composition effects

Targeting Survivin expression induces cell proliferation defect and subsequent cell death involving mitochondrial pathway in myeloid leukemic cells