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62 Moreover, small molecule inhibitors of LDHA, such as GSK2837808A, FX-11, galloflavin, and N-hydroxyindole-based compounds, inhibit pyruvate-to-lactate conversion, and may possess the potential to regulate lactylation

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NAD + accumulation may inhibit the phosphorylation of different Tau protein sites by inhibiting the activity of Cdk5-p25 complex