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One prominent example of these disorders is the cryopyrin-associated periodic syndrome (CAPS), which comprise a spectrum of disorders caused by gain-of-function mutations in the NLRP3 gene (also referred to cold-induced autoinflammatory syndrome 1, or CIAS1 gene) on chromosome 1q44, which encodes cryopyrin

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Inflammation plays a crucial role in neurodegenerative diseases as a component of the innate immune response, and oxidative stress is an important hallmark [56]