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For copper deficiency: Copper supplementation in the appropriate form and dose

Can help modulate oxidative stress signaling and reduce reactive-burden markers in experimental settings

However, existing research still faces issues such as insufficient reliability in demonstrating clinical causal relationships, overreliance on animal models, and inadequate elucidation of underlying mechanisms

Agents should induce NO-overactivity and over-release, increased free radical formation, and severe disturbances (including neurodegenerative diseases) [191]

III & Igarashi, P

Less suitable candidates Those requiring immediate results: While some notice first-dose effects, DSIP works best with consistent use over weeks