Dysregulation of these pathways contributes to various cell death diseases, such as cancer, neurodegenerative diseases, and ischemic injury, where either evasion or excessive activation of cell death disrupts normal function
Glutathione, oxidative stress and neurodegeneration
Extracellular glutathione peroxidase is higher than normal in the lungs of patients with asthma
At the end of the experiment, all mice were euthanized humanely using carbon dioxide inhalation followed by cervical dislocation
and the content of proteins was quantified with BCA assay (Thermo Fisher Scientific, Waltham, MA, USA)
Ritz SA, Wan J, Diaz-Sanchez D: Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract