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In aged research models, Epithalon administration has been associated with restored nighttime melatonin peaks, improved circadian rhythm amplitude, and normalization of cortisol secretion patterns

Moreover, systemic perfusion containing 1,25(OH)2D or 25(OH)D delayed the development of tumors and reduced lung metastasis

1.1 Methodology This review systematically examined PubMed, Scopus, Web of Science, and Google Scholar for original research on HTY and its primary metabolites published from 1995 to 2025

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Their use here is for informational and illustrative purposes only

doi: 10.3390/microorganisms12020234 129 HartantiATKurniawanBCGunawanAW