Such events can precipitate extensive cardiomyocyte death, resulting in pronounced cardiac function deterioration and, in severe cases, life-threatening complications ( Myocardial ischemia constitutes the predominant mechanism underlying CHD pathophysiology and serves as the central pathological process
AMP incubation with DTT at neutral pH for 24 h resulted in the formation of its DKP-AMP, showing the same reactivity than AX through intramolecular cyclization ( Figure 3A and Figure S3 )
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Pediatrics/adolescents safe levels have been evaluated in adults, but not in children