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Barrier dysfunction is documented and accepted in conditions such as celiac disease and Crohn's disease , and the phenomenon has been studied since the 1970s

PMID: 33159818

It is also important to test our approach on P

All procedures were carried out in accordance with Fujian Medical University animal care and welfare guidelines and institutional animal welfare regulations, and were approved by the Institutional Animal Care and Use Committee of Fujian Medical University (Approval No