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Plays a role in the immune system by detecting antigens and triggering immune responses against invaders

In their study, human-derived monocytes were treated with either PMA, pharmacologic G6PD inhibitor 6-AN, G6PD-silencing siRNA, siRNA + hyperglycemia, or hyperglycemia alone and then inspected for changes in monocyte polarization without an immunogenic stimulus

Li J, Cordero P, Nguyen V, Oben JA

cerevisiae , the MAPK cascade regulates cell wall biosynthesis, a key determinant of cell morphology, as well as the overall cell cycle

Each gene expression experiment was performed at least 3 times and calculations were made from measurements of 3 replicates of each sample

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