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Proteomic analyses indicate that DJ-1 activates the Nrf2 pathway, modulating antioxidant responses and metabolic enzymes to counteract oxidative stress in transgenic zebrafish (Fryset et al., 2018)

Ma L, Lin XM

10.1016/j.pt.2020.03.010 Trends Parasitol

Combined with its unique ability to replenish glutathione directly within the delicate lung epithelial cells, NAC protects pulmonary tissues from ongoing oxidant damage caused by environmental irritants and immune responses

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observation of higher levels of GSSG may be due to the use of PCA as the precipitating acid as well as the detection methods