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Description

Mast Cell Activation Syndrome Treatment Conventional treatment for mast cell activation syndrome generally involves the use of pharmaceutical and over-the-counter medications to alleviate symptoms, such as the following medications: Epinephrine (such as an EpiPen) for severe reactions First generation H1 blockers diphenhydramine (Benadryl) and hydroxyzine (Vistaril) Second generation H1 blockers, including loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra) H2 blockers, such as ranitidine (Zantac) and famotidine (Pepcid) Aspirin, to block production of prostaglandin D2 and reduce flushing

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or collapse (possible anaphylaxis) Severe abdominal pain (possible pancreatitis) Signs of infection at the injection site (redness, swelling, discharge, or fever) Persistent vomiting or inability to tolerate fluids Chest pain, palpitations, or difficulty breathing Severe dizziness or loss of consciousness For non-urgent concerns, contact your GP or call NHS 111 for advice

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