These two peptides are frequently studied together, and for good reason
A modern review by Pickart and Margolina ( International Journal of Molecular Sciences , 2018) synthesises transcriptomic data showing GHK modulates the expression of a large number of human genes across repair and protective pathways the gene-regulation strand of GHK-Cu research
[8] investigated insulin regulation of total, intracellular, and cell surface GHRs and receptor biosynthesis and turnover
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Oral delivery is especially effective for GI-tract healing given the peptide's gastric origin
Prior to the targeted synthesis and study of these peptides, research into growth hormone modulation relied largely on less selective secretagogues and broader hormonal interventions
