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78,217 Notably, some reactive astrocytes, in the context of ischaemic brain damage, become actively phagocytic, thus contributing to the removal of damaged cells and assisting post-stroke regeneration

The clinical relevance of these potential interactions in humans remains uncertain, and more research is needed to determine whether berberine meaningfully affects metformin's pharmacokinetics

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Upon binding to its specific receptors, EP2 and EP4, PGE2 activates various signaling cascades, including STAT3, CREB1, and NF-B, to upregulate IL-23R expression on Th17 cells

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