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doi: 10.3390/genes12101620 39 KozieE.Otulak-KozieK.BujarskiJ

This study describes a novel biochemical mechanism by which glutathione deficiency causes epigenetic impairment of vitamin D metabolism gene in the liver and its contribution to reduced circulating levels of 25(OH)VD 3 in HFD-fed obese mice

Homocysteine may inhibit thrombomodulin expression by altering the thiol redox-regulated intracellular transport, and may inhibit thrombomodulin activity by altering the disulfide-bondrich motif inside the protein, protein C activity (Lentz, 1997

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The assay was performed in an 8 12-well microplate

After reconstitution, keep refrigerated at 28 C