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A combination of ALA (50 M) and palmitoyl-ethanolamide (5 M) could reduce OxS (overproduction of ROS and NO) and modulate the major inflammatory cytokines (IL-, IL-6,TNF, and IL-10) involved in COVID-19 infection 534

The increased expression of cytokines may be due to fungal cell wall-associated constituents such as phospholipase B, lipase, and aspartyl proteinase secreted by yeast cells [51]

FOXO4-DRI significantly improves vascular function and delays vascular aging