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Table 8: Effect of Coadministered Drugs on Rosuvastatin Systemic Exposure QD= Once daily, BID= Twice daily, TID= Three times daily, QID= Four times daily 1Single dose unless otherwise noted

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Comprehensive metabolome analyses reveal N -acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin