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2013 , e812387 (2013)

Pharmaceutical pipeline: there are no Phase 1 through Phase 3 trials of 5-Amino-1MQ itself registered on ClinicalTrials.gov as of June 2026

It has been reported that AFBO, with highly activity and electrophilicity, can covalently bind to DNA and serum albumin lysine to form AFB 1 -N7-GUA and lysine adducts, resulting in DNA lesions, mutations and cytotoxicity [4, 6]

These findings support the notion that metabolic defects are present in both neural and extra-neural tissues, but the functional consequences may differ

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doi:10.1002/14356007.a26_767