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More specifically, cellular replication of the cytochrome C Bax protein triggers the activation of the caspase-3 protease, which is the primary molecular mechanism of apoptosis (220)

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sAP, serum alkaline phosphatase

doi: 10.3748/wjg.v28.i1.23

A novel glucagon-like peptide-1 (GLP-1)/glucagon hybrid peptide with triple-acting agonist activity at glucose-dependent insulinotropic polypeptide, GLP-1, and glucagon receptors and therapeutic potential in high fat-fed mice

In severe cases, skin and underlying tissue can suffer necrosis (tissue death), requiring antibiotics or surgery to treat