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The institutional review board of Chonnam National University Hospital approved the study protocol (CNUH-EXP-2021-431)

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As a matter of fact, MTHFR C677T polymorphism has been shown to increase risk of PD in Europeans (92, 93), and Asians (93) with conflicting data (92), and has been shown to significantly increase risk of Migraine in Asians (94)

Duarte-Silva S, Maciel P

H., MacIsaac, R