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deep anesthesia was confirmed by flaccidity and the absence of a pain response to a hind-limb pinch, after which cervical dislocation was carried out

doi: 10.1021/acschembio.5b00245 54 DollSPronethBTyurinaYYPanziliusEKobayashiSIngoldIet al

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4.4 Socioeconomic burden and the need for cost-effective therapies Beyond its medical impact, AD imposes a substantial socioeconomic burden, affecting patients, caregivers, and healthcare systems

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Effectively delivered means what actually reaches your bloodstream