1997 Cancer Epidemiol
High temperatures can cause the tobacco to dry out, while fluctuating temperatures can lead to condensation inside the pack, which can ruin the cigarettes
Jarvik ME, Madsen DC, Olmstead RE, Iwamoto-Schaap PN, Elins JL, Benowitz NL (2000)
They present antigens to recruit and activate lymphocytes and produce cytotoxic molecules such as hydrogen peroxide, oxygen ions, nitric oxide, and TNF to induce target cell death and engage in ADCC
New federal legislation mandated health warnings on cigarette packs (1965), banned advertising cigarettes on radio and TV (1971), and required states to pass laws setting age 18 as the minimum age for purchasing cigarettes (1992)
Some tobacco companies have included reducing the amount of cigarette butts in the environment as part of their sustainability goals, but these industries not only create the waste in the first place, but they are now trying to cover that up through misleading public displays of eco-activism, also known as greenwashing