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Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

Barcoded reverse transcription primers were used to capture the polyadenylated mRNA

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GPX4 is a key regulator of the classical pathway of the GSHGPX4 ferroptosis pathway

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However, key translational challenges remain, including poor bioavailability, methodological inconsistencies, and a scarcity of high-quality clinical evidence