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Despite these assumptions, no direct evidence exist supporting bacterial or endotoxin transport through the paracellular pathway

These results show CHO R C5/Bcl-2 cells to be less sensitive to tamoxifen collateral sensitivity than CHO R C5 cells (IC 50 0.593 0.28 M versus 1.49 0.23 M, respectively), consistent with a protective effect likely due to the overexpression of recombinant huBcl-2

doi:10.1128/JB.187.11.3839-3847.2005 49

This agent has been studied in a 14-week trial and showed improvement in gouty symptoms.15 This agent may have a future role in preventing gout attacks when patients are started on a uric acid lowering agent but can take the usual prophylactic agents against the attacks that often are an early result of this therapy (for example, they can't use colchicine)

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