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Histologically, chronic pefloxacin treatment increased the ratio of cells with round nuclei, a phenomenon seen in tendinopathy (Figures 4D, E)

Moreover, a recently published retrospective case series described 12 adolescents with vitamin B 12 and folate deficiency along with increased homocysteine levels who were admitted to a child and adolescent psychiatry clinic, mainly due to depression and anxiety symptoms [39]

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