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(2021) demonstrated that activation of BNIP3-mediated mitophagy attenuates dopaminergic neuronal damage in both MPP + -tinduced cells and MPTP-induced Parkinsons disease mouse models

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Mol Cell 2016;61:520-34

The medication reduces the risk of side effects like abnormal growth (acromegaly) or severe insulin resistance that can occur with excessive hormone levels

Moreover, it is a time-consuming procedure with a relatively low success rate, posing challenges for large-scale studies at a population level