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Dihexa treatment protected hair cells from acute aminoglycoside treatment (neomycin or gentamicin) but conferred no protection from chronic gentamicin or cisplatin exposure

These studies generally demonstrate favorable safety profiles, although their therapeutic efficacy is often limited by poor aqueous solubility, rapid metabolism, and low systemic bioavailability

Both compounds promote hair growth, but they accomplish this through different mechanisms and with different profiles of effects