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As a multimodal neuroregenerative agent, catalpol also targets the insulin-like growth factor-1 (IGF-1) signaling pathway to drive axonal repair and functional recovery post-stroke (Liu et al., 2025)

[DOI] [PubMed] [Google Scholar] 55.Shukla V., Mishra S.K., Pant H.C

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This is evidenced by the fact that endogenous -Syn levels lead to mitochondrial fragmentation (Kamp et al., 2010), and -Syn is forcibly delivered to the mitochondrial membrane, leading to mitochondrial fragmentation (Pozo et al., 2017)

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