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Compared with the Con group, DSS-treated mice showed reduced T cell mean fluorescence intensity, accompanied by increased IFN- + T and IL-17 + T mean fluorescence intensity, indicating T-cell-mediated pro-inflammatory activation in UC

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Nat Rev Dis Prim (2020) 6:22

An open-label extension of the trial showed that the long-term application of DMAE gel for up to 1 year was associated with a good safety profile

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