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In this context, growing interest and several research studies have been dedicated to determining the potential role of nutraceuticals in the management of ED, by reporting a variable degree of therapeutic success

Fujii T, Naing A, and Rolfo C, et al (2018) Biomarkers of response to immune checkpoint blockade in cancer treatment Crit Rev Oncol Hematol 130 108120 PMID: 30196907 19

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Furthermore, several organic acids (citric acid, malic acid, ascorbic acid) and phenylpropanoids (caffeic acid 3--D-glu, naringenin) also exhibited high VIP scores, contributing to group discrimination and likely supporting redox homeostasis and defense pathways