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doi: 10.4103/jfmpc.jfmpc_467_20 [DOI] [PMC free article] [PubMed] [Google Scholar] 168.Yousofzai BS, Alami M, Sheela SK, et al

It was not based on our understanding now of how biology works

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Because Cagrilintide is a structurally modified amylin analog with enhanced stability, it allows researchers to investigate receptor activation dynamics and downstream signaling events in controlled biochemical systems with greater experimental consistency than native amylin peptides

However, it is still unknown if soluble uric acid (sUA) activates the inflammasome complex and lead to IL-1 production

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