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Senomorphics: A class of therapeutics that reduce the toxicity of senescent cells by dampening their secretome (e.g., SASP)

Several studies have shown that anti-EpCAM antibodies limit therapeutic efficacies as the results of showing dose- and target-dependent in metastatic cancers, short serum half-life, altered EpCAM expression pattern, and differential cleavage and localization of EpICD in cancer cells (Fig

Peptide anti-inflammatory mechanisms: BPC-157, GHK-Cu, Thymosin Beta-4 reduce inflammation through specific pathway modulation

however, compensatory glycolysis and glucose uptake were observed in response to OXPHOS inhibition (6)

Sourkes TL (2009) The discovery of neurotransmitters, and applications to neurology