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In a pooled analysis of two retrospective, observational studies (including the phase 3b study [11]), plasma ammonia levels were reduced to a significantly greater extent with carglumic acid + ammonia scavengers than with ammonia scavengers alone at all timepoints during the first 72 h of treatment, except 1224 h (Table 3) [12]

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Vitamin C regenerates oxidised glutathione (GSSG) back to active GSH via an indirect recycling mechanism

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