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In addition, a study conducted in BV2 murine microglia cells, which served as a representative cell specimen for brain microglia, showed that the upregulation of antioxidant/detoxification proteins by SFN was associated with enhanced resistance of microglial cells to heat-induced toxicity and removal of ROS during microglial cell activation (90)

J Rheumatol 40(7):10891096 Kyoung-Jin M, Kyounghwa C, Taeg KK (2011) Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells

Dexamethasone quenched the labile iron pool by fostering an GR1-dependent increase in iron storage within ferritin, which also correlated to a reduced expression of the lysosomal iron import protein CD44

It also contributes to collagen production, improving skin density and texture and reducing water loss

Glutathione is often called the master antioxidant. It is a peptide, which is a small protein, naturally produced in every cell of your body