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Children presenting neurological signs or symptoms, those unable to take oral medication, individuals with known malabsorption syndromes, infants under 6 months old, and patients using medications that may interfere with vitamin B12 absorption are typically treated with a parenteral protocol (1)

HMB: A leucine metabolite known for muscle growth enhancement and breakdown prevention

The lack of information is because of insufficient human clinical trials

Martin Marshall (@MartinRCGP) Tweeted: 2 emails from friends overnight saying the same thing, one a GP and local NHS leader and the other a clinical academic

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Megadoses of B12 can lead to headaches, nausea, diarrhea, vomiting, and flushing, he says