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It also attenuates systemic inflammation caused by the enhancement of TLR4 and myeloid differentiation factor 88 (MyD88), suppressing the release of inflammatory factors such as TNF- and IL-1

It is involved in detoxification processes, immune system support, and may aid in the metabolism of toxins and carcinogens

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Therefore, patients had a qualifying ECOG performance status score to meet the VA guidelines before initiating checkpoint inhibitor therapy

Zhongjun Du, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Haffke, M