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Editorial on the Research Topic Gut permeability-related endotoxemia and cardiovascular disease: A new clinical challenge Introduction Emerging evidence indicates that gut dysbiosis is a risk factor for cardiovascular disease (CVD) in type 1 diabetes mellitus ( and tumour necrosis factor alpha ( The human body encompasses local and systemic mechanisms to counteract LPS translocation or to detoxify it

Sikiric et al., 2020b), along with suggested significance of NO-synthase and the basal formation of NO in stomach mucosa, greater than that seen in other tissues (Whittle et al., 1992), BPC 157 exhibits a general, effective competing with both L-arginine analogs (i.e., L-NAME) and L-arginine (Sikiric et al., 2014)

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