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Teschke R, Uetrecht J (2021) Mechanism of idiosyncratic drug induced liver injury (DILI): Unresolved basic issues

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Gabriel SE, Crowson CS, OFallon M

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The S-acetyl modification serves two purposes: it makes the molecule more stable and resistant to degradation in the GI tract, and it may help the molecule cross cell membranes more easily than unmodified reduced glutathione