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Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition

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For a broader primer on how researchers approach compound selection generally, see our complete peptide research guide

Tyrance serves as an advisor to a number of healthcare startups and evaluates patented technologies in medicine and healthcare for their commercialization potential

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