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It has been demonstrated that GPX4 is significant in protecting Treg cells from undergoing lipid peroxidation and ferroptosis, thereby contributing to maintaining immune homeostasis (Xu et al., 2021)

30: 347 Endo A, Watanabe T

Cell death machinery of erythrocytes should be further investigated to explore the possibility of its pharmacological targeting

Interplay between SIRT proteins and tumour suppressor transcription factors in chemotherapeutic resistance of cancer

Sitthideatphaiboon P, Galan-Cobo A, Negrao MV, Qu X, Poteete A, Zhang F, Liu DD, Lewis WE, Kemp HN, Lewis J, Rinsurongkawong W, Giri U, Lee JJ, Zhang J, Roth JA, Swisher S , Heymach JV