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Notably, one participant with a history of B12-responsive acne developed lesions following B12 administration during the study

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Depending on how severe it is, it may take weeks or months before the symptoms are gone

Time needed for improvement ranges from a few days to several weeks, depending on the individual

The combination of a PPI and metformin would absolutely require regular laboratory tests for vitamin B12

The practical implication: if you dose 5-amino-1mq at night, you need a longer fasting window (minimum six hours post-meal) to approach the same bioavailability as morning dosing