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Glutathione (GSH) quickly combines with NAPQI, and the resulting complexes are converted to nontoxic cysteine or mercaptate conjugates, which are eliminated in the urine
Xiong M, Zhang Q, Hu W, Zhao C, Lv W, Yi Y
The advantage of our measurement of the Glutathione Index (GSH/GSSG) is therefore, that it shows changes in GR activity, not only due to higher/lower GR gene activity but also due to the absence of the reaction cofactor NADP. As a result, dementia patients have a lower potential to dynamically fight free radicals and will have a worse GSH/GSSG, which we call the Glutathione Index (7)
At low doses, this can represent a meaningful percentage of your dose
Acknowledgements This work was partially supported by grants from JSPS (KAKENHI Grant Numbers JP21K08032 and 24K11270) to KS