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Glut1deficiency suppresses the expression of low-density LRP1 and reduces CBF, suggesting a connection between CBF, A clearance, and glucose metabolism disturbances [163]

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Early analysis from a phase 3 REDEFINE 1 trial showed the once-weekly Cagrilintide monotherapy injection helped patients reduce their weight by 11.8% on average after 68 weeks, compared to 2.3% for those on placebo, the company said

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