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This study aimed to investigate the therapeutic effect of exogenous GHK-Cu on UC mice and explore its mechanism

Dehydration and blood sugar fluctuations are the usual culprits

This is relevant not only for side effect management but for fertility: dutasteride is contraindicated in women of childbearing age and in men who may be trying to conceive, given its effects on DHT-dependent fetal development

That's personal preference

However, the ideal frequency can vary based on the severity of the deficiency and your response to treatment

When B12 is taken multiple times throughout the day, 2-5 g of B12 per intake can be sufficient