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Collectively, work across multiple independent laboratories have reported on both amyloid and tau transgenic AD mouse models, postmortem human brain tissue from two distinct tau-expressing neurodegenerative conditions, and three senolytic compounds (Table 1)

Cognitive decline: Research in patients with mild cognitive impairment and early dementia shows Semax slows progression and improves function in some cases

The negative charge in RSS species is mostly located on the outer nucleophilic sulfur atom

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Nonetheless, further research is required to optimize these systems and evaluate their safety and efficacy in clinical settings