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This product is supplied strictly as a research compound formulation and is not intended for human or veterinary use

Individuals struggling with diabetic nephropathy might experience a more rapid decline in kidney function when they take unusually high doses of vitamin B-12

There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

In diabetes research, it is used to investigate the pathogenesis of type 2 diabetes and validate potential therapeutic effects

A meta-analysis of four observational studies, following a total of 7,475 older individuals for 3 to 16 years, found a weak association between an elevation in vitamin B 12 of 50 pmol/L in blood and a reduction in fracture risk (114)