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Once growth hormone binds to these receptors, it might activate enzymes such as hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL), which facilitate the breakdown of stored triglycerides into free fatty acids and glycerol

In summary, leptin acts as an important mediator in the pathogenesis of MASLD, serving as both a marker of obesity and a regulator of inflammation and IR

It can be administered rectally in patients that cannot take oral medications

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This diversity in localization makes it essential to adjust lipid type and process conditions based on molecular characteristics