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Bile acids activate FXR to inhibit ferroptosis, and FXR activation significantly reduces lipid peroxidation by upregulating ferroptosis gatekeepers GPX4, FSP1, PPAR, SCD1, and ACSL3, thereby acting as a guardian of ferroptosis (Tschuck et al., 2023)

Insulin can enhance norepinephrine-mediated melatonin production in the pineal gland of rats [138]

In another set of rats that were genetically modified to age quickly, FOXO4-DRI caused hair that was lost due to age to grow back

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Acta Dermato-Venereologica 103: adv00890