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The International Journal of Biochemistry & Cell Biology

Design principles of the paradoxical feedback between pancreatic alpha and beta cells

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In contrast to phytoestrogens, these chemicals tend to bioaccumulate and induce persistent and refractory effects, even though their environmental concentrations oscillate in a relatively low range (Rebuli et al., 2014), leading to consider its potential for inducing changes in the cellularity and/or functionality of diverse areas of the brain or even reduce the sensitivity of others to endogenous estrogen